WyBlog

Boehringer Ingelheim is putting the finishing touches on a pill designed to reawaken desire by blunting female inhibitions. Unlike Viagra, which targets the mechanics of sex by boosting blood flow to the penis, this drug works on the brain.

The desire drug, the focus of a meeting on sexual disorders in Lyon this week, has the potential to revolutionize sexual medicine much as Pfizer Inc.'s blue pill did a decade ago.

"This drug has the potential to finally open the door to acceptance of the idea that decreased desire can be something that involves a dysfunctional way the brain works, and not only a bad partner," said Jim Pfaus, a neurologist at Concordia University in Montreal, who conducted early tests of the drug in rats. "Of course it's in your head."

The U.S. market for medicines to rekindle female libido could be bigger than the $2 billion a year in U.S. sales for erectile dysfunction treatments because more women report sexual problems, BioSante Pharmaceuticals chief executive officer Stephen Simes estimated last year.

The German company is taking a page from Pfizer's book. The U.S. drugmaker broadened the appeal of Viagra in 1998 by steering clear of the word "impotence" and saying the blue pill addressed a disease called erectile dysfunction. Boehringer is avoiding potentially offensive words such as frigidity and refers to the problem its pill cures by its clinical name, hypoactive sexual desire disorder, or HSDD.

"An increasing body of evidence shows that hypoactive sexual desire disorder causes substantial emotional distress," said Heike Specht, a spokesman for the company. The drugmaker "has conducted late-stage clinical trials in over 5,000 women from which we hope will result the first available pharmaceutical treatment."

A Boehringer survey of 31,000 U.S. women aged 18 and above found that one in 10 expressed distress because of diminished sex drive.